Interleukin-4 receptor alpha chain and STAT6 signaling inhibit gamma interferon but not Th2 cytokine expression within schistosome granulomas.

Metwali, Ahmed

Interleukin-4 receptor alpha chain and STAT6 signaling inhibit gamma interferon but not Th2 cytokine expression within schistosome granulomas. [electronic resource] - Infection and immunity Oct 2002 - 5651-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0019-9567

10.1128/IAI.70.10.5651-5658.2002 doi


Animals
Cytokines--biosynthesis
Granuloma--genetics
Interferon-gamma--biosynthesis
Interleukin-12--biosynthesis
Interleukin-4--biosynthesis
Interleukin-5--biosynthesis
Killer Cells, Natural--immunology
Mice
Mice, Inbred BALB C
Mice, Knockout
RNA, Messenger--genetics
Receptors, Interleukin-4--deficiency
STAT6 Transcription Factor
Schistosomiasis mansoni--genetics
Signal Transduction
Th1 Cells--immunology
Th2 Cells--immunology
Trans-Activators--deficiency