TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation.

Long, Xiaomeng

TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. [electronic resource] - Current biology : CB Sep 2002 - 1448-61 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0960-9822

10.1016/s0960-9822(02)01091-6 doi


Adaptation, Physiological--genetics
Alleles
Animals
Atrophy
Caenorhabditis elegans--genetics
Caenorhabditis elegans Proteins--genetics
Eukaryotic Initiation Factor-2--deficiency
Eukaryotic Initiation Factor-4G--deficiency
Gene Expression Regulation, Developmental
Gene Targeting
Genes, Lethal
Genetic Complementation Test
Intestines--growth & development
Larva
Phenotype
Phosphotransferases (Alcohol Group Acceptor)--genetics
Protein Biosynthesis
RNA Interference
RNA, Messenger--genetics
Ribosomal Protein S6 Kinases, 70-kDa--deficiency
Sequence Homology, Amino Acid
Sirolimus--pharmacology
Species Specificity
Starvation