Structural basis for inhibition of protein tyrosine phosphatases by Keggin compounds phosphomolybdate and phosphotungstate.

Heo, Yong-Seok

Structural basis for inhibition of protein tyrosine phosphatases by Keggin compounds phosphomolybdate and phosphotungstate. [electronic resource] - Experimental & molecular medicine Jul 2002 - 211-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1226-3613

10.1038/emm.2002.30 doi


Binding, Competitive
Catalytic Domain
Crystallography, X-Ray
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical
Edetic Acid--pharmacology
Enzyme Inhibitors--pharmacology
Humans
Inhibitory Concentration 50
Kinetics
Models, Molecular
Molybdenum--pharmacology
Phosphoric Acids--pharmacology
Protein Structure, Tertiary
Protein Tyrosine Phosphatases--antagonists & inhibitors
Substrate Specificity
Tungsten Compounds--pharmacology