Chronic muscle pain induced by repeated acid Injection is reversed by spinally administered mu- and delta-, but not kappa-, opioid receptor agonists.

Sluka, Kathleen A

Chronic muscle pain induced by repeated acid Injection is reversed by spinally administered mu- and delta-, but not kappa-, opioid receptor agonists. [electronic resource] - The Journal of pharmacology and experimental therapeutics Sep 2002 - 1146-50 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-3565

10.1124/jpet.102.033167 doi


3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer--pharmacology
Analgesics, Non-Narcotic--pharmacology
Analgesics, Opioid--pharmacology
Animals
Behavior, Animal--drug effects
Benzamides--pharmacology
Chronic Disease
Dose-Response Relationship, Drug
Enkephalin, Ala(2)-MePhe(4)-Gly(5)---pharmacology
Hydrochloric Acid
Hydrogen-Ion Concentration
Hyperalgesia--chemically induced
Injections, Spinal
Morphine--pharmacology
Muscular Diseases--chemically induced
Pain Threshold--drug effects
Physical Stimulation
Piperazines--pharmacology
Rats
Receptors, Opioid, delta--agonists
Receptors, Opioid, kappa--agonists
Receptors, Opioid, mu--agonists