The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines.

Kuo, Po-Lin

The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines. [electronic resource] - Life sciences Sep 2002 - 1879-92 p. digital

Publication Type: Journal Article

0024-3205

10.1016/s0024-3205(02)01900-8 doi


Aloe--chemistry
Animals
Anthraquinones
Apoptosis--drug effects
Blotting, Western
Carcinoma, Hepatocellular--pathology
Cell Cycle--physiology
Cell Division--physiology
Emodin--pharmacology
Enzyme-Linked Immunosorbent Assay
Gene Expression Regulation, Neoplastic--drug effects
Genes, bcl-2--genetics
Genes, p53--physiology
Nucleosomes--chemistry
Oncogene Protein p21(ras)--physiology
Rats
Receptors, Lipoprotein--biosynthesis
Tumor Cells, Cultured
fas Receptor--metabolism