Effects of cacao liquor proanthocyanidins on PhIP-induced mutagenesis in vitro, and in vivo mammary and pancreatic tumorigenesis in female Sprague-Dawley rats.

Yamagishi, Megumi

Effects of cacao liquor proanthocyanidins on PhIP-induced mutagenesis in vitro, and in vivo mammary and pancreatic tumorigenesis in female Sprague-Dawley rats. [electronic resource] - Cancer letters Nov 2002 - 123-30 p. digital

Publication Type: Comparative Study; Journal Article

0304-3835

10.1016/s0304-3835(02)00276-8 doi


Adenocarcinoma--chemically induced
Adenoma--chemically induced
Animals
Anthocyanins--administration & dosage
Anticarcinogenic Agents--isolation & purification
Antineoplastic Agents, Phytogenic--administration & dosage
Biotransformation
Cacao--chemistry
Carcinogens--toxicity
Catechin--isolation & purification
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Female
Flavonoids
Imidazoles--toxicity
Mammary Neoplasms, Experimental--chemically induced
Microsomes, Liver--metabolism
Mutagenesis--drug effects
Mutagenicity Tests
Organ Specificity
Pancreatic Neoplasms--chemically induced
Phenols--isolation & purification
Phytotherapy
Plant Extracts--pharmacology
Polymers--isolation & purification
Proanthocyanidins
Rats
Rats, Sprague-Dawley
Salmonella typhimurium--drug effects