A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5.

Shin, Hye Joo

A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5. [electronic resource] - Bioorganic & medicinal chemistry letters Sep 2002 - 2313-6 p. digital

Publication Type: Journal Article

0960-894X

10.1016/s0960-894x(02)00401-8 doi


3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitors
3',5'-Cyclic-GMP Phosphodiesterases--antagonists & inhibitors
Animals
Cyclic Nucleotide Phosphodiesterases, Type 3
Cyclic Nucleotide Phosphodiesterases, Type 4
Cyclic Nucleotide Phosphodiesterases, Type 5
Dose-Response Relationship, Drug
Enzyme Inhibitors--chemistry
Flavonoids--chemistry
Inhibitory Concentration 50
Kinetics
Rats
Sophora--chemistry
Structure-Activity Relationship