The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation.

Tan, Seng-Lai

The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation. [electronic resource] - The Journal of biological chemistry Sep 2002 - 36109-17 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M205109200 doi


Amino Acid Motifs
Binding Sites
Catalysis
Catalytic Domain
DNA, Complementary--metabolism
Dimerization
Escherichia coli--metabolism
Gene Library
Glutathione Transferase--metabolism
Humans
Models, Biological
Phenotype
Phosphoprotein Phosphatases--metabolism
Phosphorylation
Precipitin Tests
Protein Binding
Protein Biosynthesis
Protein Isoforms
Protein Phosphatase 1
Protein Structure, Tertiary
Saccharomyces cerevisiae--metabolism
Sequence Analysis, DNA
Two-Hybrid System Techniques
eIF-2 Kinase--metabolism