PEG chains increase aspermatogenic and antitumor activity of RNase A and BS-RNase enzymes.

Matousek, Josef

PEG chains increase aspermatogenic and antitumor activity of RNase A and BS-RNase enzymes. [electronic resource] - Journal of controlled release : official journal of the Controlled Release Society Jul 2002 - 29-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0168-3659

10.1016/s0168-3659(02)00082-2 doi


Animals
Antibody Formation--drug effects
Antineoplastic Agents--chemistry
Antispermatogenic Agents--chemistry
Cattle
Drug Screening Assays, Antitumor
Endoribonucleases--chemistry
Humans
Injections, Intraperitoneal
Injections, Subcutaneous
Male
Melanoma, Experimental--drug therapy
Mice
Mice, Inbred ICR
Mice, Nude
Polyethylene Glycols--chemistry
Ribonuclease, Pancreatic--chemistry
Semen--chemistry
Spermatogenesis--drug effects
Testis--drug effects