Coincident elevation of cAMP and calcium influx by PACAP-27 synergistically regulates vasoactive intestinal polypeptide gene transcription through a novel PKA-independent signaling pathway.

Hamelink, Carol

Coincident elevation of cAMP and calcium influx by PACAP-27 synergistically regulates vasoactive intestinal polypeptide gene transcription through a novel PKA-independent signaling pathway. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Jul 2002 - 5310-20 p. digital

Publication Type: Journal Article

1529-2401


Animals
Calcium Channel Blockers--pharmacology
Calcium Signaling
Cattle
Cells, Cultured
Chromaffin Cells--drug effects
Colforsin--pharmacology
Cyclic AMP--biosynthesis
Cyclic AMP-Dependent Protein Kinases--metabolism
Drug Synergism
Humans
MAP Kinase Signaling System
Mitogen-Activated Protein Kinases--metabolism
Neuropeptides--pharmacology
Pituitary Adenylate Cyclase-Activating Polypeptide
Potassium--pharmacology
RNA, Messenger--biosynthesis
Second Messenger Systems
Transcriptional Activation
Tumor Cells, Cultured
Vasoactive Intestinal Peptide--metabolism