Transcription factor Sp1 phosphorylation induced by shear stress inhibits membrane type 1-matrix metalloproteinase expression in endothelium.

Yun, Sangseob

Transcription factor Sp1 phosphorylation induced by shear stress inhibits membrane type 1-matrix metalloproteinase expression in endothelium. [electronic resource] - The Journal of biological chemistry Sep 2002 - 34808-14 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M205417200 doi


Animals
Base Sequence
Cells, Cultured
DNA
DNA-Binding Proteins--metabolism
Early Growth Response Protein 1
Electrophoretic Mobility Shift Assay
Endothelium, Vascular--enzymology
Immediate-Early Proteins
Matrix Metalloproteinases, Membrane-Associated
Metalloendopeptidases--physiology
Nogalamycin--pharmacology
Phosphorylation
Promoter Regions, Genetic
RNA, Messenger--genetics
Rats
Rats, Sprague-Dawley
Sp1 Transcription Factor--genetics
Stress, Physiological--metabolism
Transcription Factors--metabolism