Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats.

Freshwater, Jason D

Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. [electronic resource] - Diabetes Jul 2002 - 2249-55 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0012-1797

10.2337/diabetes.51.7.2249 doi


Animals
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Blood Glucose--metabolism
Body Weight
Cyclooxygenase 1
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--administration & dosage
Diabetes Mellitus, Experimental--physiopathology
Dinoprostone--cerebrospinal fluid
Endothelin Receptor Antagonists
Female
Formaldehyde--toxicity
Hyperalgesia--cerebrospinal fluid
Indomethacin--pharmacology
Injections, Spinal
Isoenzymes--metabolism
Membrane Proteins
Pain--chemically induced
Prostaglandin-Endoperoxide Synthases--cerebrospinal fluid
Rats
Rats, Sprague-Dawley
Receptor, Endothelin A
Reference Values
Spinal Cord--enzymology