Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

Garden, Gwenn A

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Jun 2002 - 4897-905 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1529-2401


Animals
Ataxin-7
Cell Nucleus--pathology
Gait Ataxia--etiology
Inclusion Bodies--pathology
Kinetics
Mice
Mice, Transgenic
Mutation
Nerve Tissue Proteins--genetics
Peptides--genetics
Purkinje Cells--pathology
Spinocerebellar Degenerations--etiology