Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

Malliri, Angeliki

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours. [electronic resource] - Nature Jun 2002 - 867-71 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0028-0836

10.1038/nature00848 doi


9,10-Dimethyl-1,2-benzanthracene--pharmacology
Animals
Apoptosis
Cell Division--drug effects
Disease Progression
Gene Dosage
Genotype
Guanine Nucleotide Exchange Factors
Immunohistochemistry
Keratins--analysis
Mice
Mice, Knockout
Proteins--genetics
Skin Neoplasms--enzymology
T-Lymphoma Invasion and Metastasis-inducing Protein 1
Tetradecanoylphorbol Acetate--pharmacology
ras Proteins--metabolism