Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety.

Vahle, John L

Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety. [electronic resource] - Toxicologic pathology - 312-21 p. digital

Publication Type: Journal Article

0192-6233

10.1080/01926230252929882 doi


Animals
Bone Density--drug effects
Bone Neoplasms--chemically induced
Drug Evaluation, Preclinical
Female
Humans
Hyperplasia--chemically induced
Injections, Subcutaneous
Male
Osteoblastoma--chemically induced
Osteoma--chemically induced
Osteosarcoma--chemically induced
Parathyroid Hormone--administration & dosage
Peptide Fragments--administration & dosage
Rats
Rats, Inbred F344
Recombinant Proteins--administration & dosage
Time Factors