Spinal cord neuroplasticity following repeated opioid exposure and its relation to pathological pain.

Mao, J

Spinal cord neuroplasticity following repeated opioid exposure and its relation to pathological pain. [electronic resource] - Annals of the New York Academy of Sciences Mar 2001 - 175-84 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review

0077-8923

10.1111/j.1749-6632.2001.tb05823.x doi


Analgesics--pharmacology
Analgesics, Opioid--pharmacology
Animals
Benzamides--therapeutic use
Dizocilpine Maleate--therapeutic use
Drug Tolerance
Hot Temperature--adverse effects
Humans
Hyperalgesia--drug therapy
Morphine--pharmacology
Multiple Chemical Sensitivity--physiopathology
N-Methylaspartate--toxicity
Narcotics--pharmacology
Nerve Degeneration--chemically induced
Nerve Tissue Proteins--drug effects
Neuralgia--physiopathology
Neuronal Plasticity--drug effects
Nitric Oxide--physiology
Phosphorylation
Poly(ADP-ribose) Polymerases--physiology
Posterior Horn Cells--drug effects
Protein Kinase C--physiology
Protein Processing, Post-Translational
Rats
Receptors, N-Methyl-D-Aspartate--drug effects
Receptors, Opioid--drug effects
Receptors, Opioid, mu--drug effects
Sciatic Nerve--injuries
Spinal Cord--drug effects