Ethanol and LPS modulate NF-kappaB activation, inducible NO synthase and COX-2 gene expression in rat liver cells in vivo.
Spitzer, Judy A
Ethanol and LPS modulate NF-kappaB activation, inducible NO synthase and COX-2 gene expression in rat liver cells in vivo. [electronic resource] - Frontiers in bioscience : a journal and virtual library May 2002 - a99-108 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
1093-9946
10.2741/A744 doi
Animals
Binding, Competitive
Cells, Cultured
Cyclooxygenase 2
Electrophoretic Mobility Shift Assay
Endothelium--cytology
Ethanol--pharmacology
Female
Gene Expression Regulation, Enzymologic--drug effects
Hepatocytes--cytology
Interleukin-6--blood
Isoenzymes--genetics
Kinetics
Kupffer Cells--cytology
Lipopolysaccharides--pharmacology
Liver--cytology
Male
NF-kappa B--drug effects
Nitric Oxide Synthase--genetics
Nitric Oxide Synthase Type II
Prostaglandin-Endoperoxide Synthases--genetics
RNA, Messenger--genetics
Rats
Rats, Sprague-Dawley
Time Factors
Ethanol and LPS modulate NF-kappaB activation, inducible NO synthase and COX-2 gene expression in rat liver cells in vivo. [electronic resource] - Frontiers in bioscience : a journal and virtual library May 2002 - a99-108 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
1093-9946
10.2741/A744 doi
Animals
Binding, Competitive
Cells, Cultured
Cyclooxygenase 2
Electrophoretic Mobility Shift Assay
Endothelium--cytology
Ethanol--pharmacology
Female
Gene Expression Regulation, Enzymologic--drug effects
Hepatocytes--cytology
Interleukin-6--blood
Isoenzymes--genetics
Kinetics
Kupffer Cells--cytology
Lipopolysaccharides--pharmacology
Liver--cytology
Male
NF-kappa B--drug effects
Nitric Oxide Synthase--genetics
Nitric Oxide Synthase Type II
Prostaglandin-Endoperoxide Synthases--genetics
RNA, Messenger--genetics
Rats
Rats, Sprague-Dawley
Time Factors