Novel mode of interference with nuclear factor of activated T-cells regulation in T-cells by the bacterial metabolite n-butyrate.

Diakos, Christos

Novel mode of interference with nuclear factor of activated T-cells regulation in T-cells by the bacterial metabolite n-butyrate. [electronic resource] - The Journal of biological chemistry Jul 2002 - 24243-51 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M200191200 doi


Butyrates--pharmacology
Calcium Signaling--physiology
Cyclic AMP--metabolism
DNA-Binding Proteins--drug effects
Humans
Interleukin-2--biosynthesis
Jurkat Cells
Lymphocyte Activation
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)--metabolism
MAP Kinase Signaling System--physiology
NF-kappa B--metabolism
NFATC Transcription Factors
Nuclear Proteins--immunology
T-Lymphocytes--immunology
Transcription Factors--drug effects