Induction of apoptosis in the lung but not in the liver of rats receiving intra-tracheal instillations of chromium(VI).

D'Agostini, Francesco

Induction of apoptosis in the lung but not in the liver of rats receiving intra-tracheal instillations of chromium(VI). [electronic resource] - Carcinogenesis Apr 2002 - 587-93 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0143-3334

10.1093/carcin/23.4.587 doi


Animals
Apoptosis
Carcinogens, Environmental
Caspase 6
Caspases--biosynthesis
Chromates--pharmacology
Chromium--administration & dosage
DNA Topoisomerases, Type II--biosynthesis
DNA, Complementary--metabolism
DNA-Binding Proteins
Deoxyribonuclease I--biosynthesis
Dose-Response Relationship, Drug
In Situ Nick-End Labeling
JNK Mitogen-Activated Protein Kinases
Liver--drug effects
Lung--drug effects
Male
Mitogen-Activated Protein Kinases--biosynthesis
Nuclear Proteins
Oligonucleotide Array Sequence Analysis
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-bcl-2
Proto-Oncogene Proteins c-mdm2
Rats
Rats, Sprague-Dawley
Reverse Transcriptase Polymerase Chain Reaction
Time Factors
Trachea--metabolism
bcl-2-Associated X Protein