Simvastatin improves endothelial function in spontaneously hypertensive rats through a superoxide dismutase mediated antioxidant effect.

Carneado, Joaquin

Simvastatin improves endothelial function in spontaneously hypertensive rats through a superoxide dismutase mediated antioxidant effect. [electronic resource] - Journal of hypertension Mar 2002 - 429-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0263-6352

10.1097/00004872-200203000-00018 doi


Animals
Antioxidants--pharmacology
Aorta--drug effects
Endothelium, Vascular--drug effects
Glutathione Peroxidase--metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Hypertension--physiopathology
In Vitro Techniques
Male
Rats
Rats, Inbred SHR--physiology
Rats, Inbred WKY
Simvastatin--pharmacology
Superoxide Dismutase--physiology
Superoxides--metabolism