Identification of the human P450 enzymes involved in the in vitro metabolism of the synthetic steroidal hormones Org 4060 and Org 30659.

Verhoeven, C H J

Identification of the human P450 enzymes involved in the in vitro metabolism of the synthetic steroidal hormones Org 4060 and Org 30659. [electronic resource] - Xenobiotica; the fate of foreign compounds in biological systems Feb 2002 - 109-18 p. digital

Publication Type: Journal Article

0049-8254

10.1080/00498250110093026 doi


Aryl Hydrocarbon Hydroxylases
Chromatography, High Pressure Liquid
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--metabolism
Humans
In Vitro Techniques
Ketoconazole--pharmacology
Kinetics
Microsomes, Liver--metabolism
Norethindrone--analogs & derivatives
Oxidoreductases, N-Demethylating--metabolism