Identification of the major metabolite of 2,5-bis(5-hydroxymethyl-2-thienyl)furan (NSC 652287), an antitumor agent, in the S9 subcellular fraction of dog liver cells.

Phillip, Lawrence R

Identification of the major metabolite of 2,5-bis(5-hydroxymethyl-2-thienyl)furan (NSC 652287), an antitumor agent, in the S9 subcellular fraction of dog liver cells. [electronic resource] - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Feb 2002 - 27-33 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1570-0232

10.1016/s0378-4347(01)00530-8 doi


Animals
Antineoplastic Agents--pharmacokinetics
Biotransformation
Dogs
Furans--pharmacokinetics
Gas Chromatography-Mass Spectrometry
Liver--cytology
Oxidation-Reduction
Spectrometry, Mass, Electrospray Ionization
Subcellular Fractions--metabolism
Thiophenes--pharmacokinetics