Emergence of resistance to protease inhibitor amprenavir in human immunodeficiency virus type 1-infected patients: selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors.
Maguire, Michael
Emergence of resistance to protease inhibitor amprenavir in human immunodeficiency virus type 1-infected patients: selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors. [electronic resource] - Antimicrobial agents and chemotherapy Mar 2002 - 731-8 p. digital
Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial
0066-4804
10.1128/AAC.46.3.731-738.2002 doi
Carbamates
Cloning, Molecular
Drug Resistance, Microbial
Drug Therapy, Combination
Furans
Genotype
HIV Core Protein p24--drug effects
HIV Infections--drug therapy
HIV Protease--genetics
HIV Protease Inhibitors--therapeutic use
HIV Reverse Transcriptase--antagonists & inhibitors
HIV-1--drug effects
Humans
Mutagenesis, Site-Directed
Nucleosides--pharmacology
Phenotype
RNA, Viral--chemistry
Reverse Transcriptase Inhibitors--therapeutic use
Reverse Transcriptase Polymerase Chain Reaction
Sulfonamides--therapeutic use
Emergence of resistance to protease inhibitor amprenavir in human immunodeficiency virus type 1-infected patients: selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors. [electronic resource] - Antimicrobial agents and chemotherapy Mar 2002 - 731-8 p. digital
Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial
0066-4804
10.1128/AAC.46.3.731-738.2002 doi
Carbamates
Cloning, Molecular
Drug Resistance, Microbial
Drug Therapy, Combination
Furans
Genotype
HIV Core Protein p24--drug effects
HIV Infections--drug therapy
HIV Protease--genetics
HIV Protease Inhibitors--therapeutic use
HIV Reverse Transcriptase--antagonists & inhibitors
HIV-1--drug effects
Humans
Mutagenesis, Site-Directed
Nucleosides--pharmacology
Phenotype
RNA, Viral--chemistry
Reverse Transcriptase Inhibitors--therapeutic use
Reverse Transcriptase Polymerase Chain Reaction
Sulfonamides--therapeutic use