Emergence of resistance to protease inhibitor amprenavir in human immunodeficiency virus type 1-infected patients: selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors.

Maguire, Michael

Emergence of resistance to protease inhibitor amprenavir in human immunodeficiency virus type 1-infected patients: selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors. [electronic resource] - Antimicrobial agents and chemotherapy Mar 2002 - 731-8 p. digital

Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial

0066-4804

10.1128/AAC.46.3.731-738.2002 doi


Carbamates
Cloning, Molecular
Drug Resistance, Microbial
Drug Therapy, Combination
Furans
Genotype
HIV Core Protein p24--drug effects
HIV Infections--drug therapy
HIV Protease--genetics
HIV Protease Inhibitors--therapeutic use
HIV Reverse Transcriptase--antagonists & inhibitors
HIV-1--drug effects
Humans
Mutagenesis, Site-Directed
Nucleosides--pharmacology
Phenotype
RNA, Viral--chemistry
Reverse Transcriptase Inhibitors--therapeutic use
Reverse Transcriptase Polymerase Chain Reaction
Sulfonamides--therapeutic use