MSH2 in contrast to MLH1 and MSH6 is frequently inactivated by exonic and promoter rearrangements in hereditary nonpolyposis colorectal cancer.

Charbonnier, Françoise

MSH2 in contrast to MLH1 and MSH6 is frequently inactivated by exonic and promoter rearrangements in hereditary nonpolyposis colorectal cancer. [electronic resource] - Cancer research Feb 2002 - 848-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


Adaptor Proteins, Signal Transducing
Carrier Proteins
Colorectal Neoplasms, Hereditary Nonpolyposis--genetics
DNA-Binding Proteins--genetics
Exons
Gene Expression Regulation, Neoplastic
Gene Rearrangement
Gene Silencing
Humans
Middle Aged
MutL Protein Homolog 1
MutS Homolog 2 Protein
Neoplasm Proteins--genetics
Nuclear Proteins
Point Mutation
Polymerase Chain Reaction--methods
Promoter Regions, Genetic--genetics
Proto-Oncogene Proteins--genetics