Weekly pulse therapy of methotrexate improves survival compared with its daily administration in MRL/lpr mice.

Asanuma, Yu

Weekly pulse therapy of methotrexate improves survival compared with its daily administration in MRL/lpr mice. [electronic resource] - European journal of pharmacology Jan 2002 - 253-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-2999

10.1016/s0014-2999(01)01555-2 doi


Animals
Antirheumatic Agents--adverse effects
Autoantibodies--immunology
Autoimmunity--drug effects
Blood Cell Count
Body Weight--drug effects
Glomerulonephritis--etiology
Kidney Function Tests
Lupus Erythematosus, Systemic--blood
Lymphatic Diseases--etiology
Male
Methotrexate--adverse effects
Mice
Mice, Inbred MRL lpr
Proteinuria--etiology
Radiography
Survival Analysis
Urea--blood