The paradoxical effect of acetaminophen on CYP3A4 activity and content in transfected HepG2 cells.

Feierman, D E

The paradoxical effect of acetaminophen on CYP3A4 activity and content in transfected HepG2 cells. [electronic resource] - Archives of biochemistry and biophysics Feb 2002 - 109-17 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0003-9861

10.1006/abbi.2001.2677 doi


Acetaminophen--pharmacology
Analgesics, Non-Narcotic--pharmacology
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--drug effects
Enzyme Stability--drug effects
Fentanyl--metabolism
Humans
Mixed Function Oxygenases--drug effects
Transfection
Tumor Cells, Cultured