Paradoxical release of nitric oxide by an L-type calcium channel antagonist, the R+ enantiomer of amlodipine.

Zhang, Xiao-Ping

Paradoxical release of nitric oxide by an L-type calcium channel antagonist, the R+ enantiomer of amlodipine. [electronic resource] - Journal of cardiovascular pharmacology Feb 2002 - 208-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0160-2446

10.1097/00005344-200202000-00007 doi


Amlodipine--chemistry
Animals
Bradykinin--pharmacology
Calcium Channel Blockers--chemistry
Calcium Channels, L-Type--metabolism
Coronary Vessels--drug effects
Dogs
In Vitro Techniques
Male
Microcirculation
Myocardium--metabolism
Nitrendipine--pharmacology
Nitric Oxide--metabolism
Nitrites--metabolism
Oxygen Consumption--drug effects
Stereoisomerism
Structure-Activity Relationship