Delocalized electronic structure of the thiol sulfur substantially prevents nucleic acid damage induced by neocarzinostatin.

Kuo, Hsiu-Maan

Delocalized electronic structure of the thiol sulfur substantially prevents nucleic acid damage induced by neocarzinostatin. [electronic resource] - Biochemistry Jan 2002 - 897-905 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0006-2960

10.1021/bi015771+ doi


Acetylcysteine--analogs & derivatives
Animals
Antimetabolites, Antineoplastic--toxicity
Cattle
DNA--chemistry
DNA Damage--drug effects
Electrochemistry
Models, Molecular
Phenols--pharmacology
Prodrugs--toxicity
Structure-Activity Relationship
Sulfhydryl Compounds--chemistry
Zinostatin--toxicity