Enzymatic resolution of trans-4-(4'-fluorophenyl)-3-hydroxymethylpiperidines, key intermediates in the synthesis of (-)-Paroxetine.

de Gonzalo, G

Enzymatic resolution of trans-4-(4'-fluorophenyl)-3-hydroxymethylpiperidines, key intermediates in the synthesis of (-)-Paroxetine. [electronic resource] - The Journal of organic chemistry Dec 2001 - 8947-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-3263

10.1021/jo010809+ doi


Acetylation
Benzene Derivatives--chemistry
Candida--enzymology
Hydrolysis
Indicators and Reagents
Lipase--chemistry
Magnetic Resonance Spectroscopy
Paroxetine--chemistry
Piperidines--chemistry
Solvents
Stereoisomerism