Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase.

MacCarthy, P A

Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase. [electronic resource] - Circulation Dec 2001 - 2967-74 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4539

10.1161/hc4901.100382 doi


Animals
Antioxidants--metabolism
Arginine--pharmacology
Ascorbic Acid--pharmacology
Biopterins--analogs & derivatives
Deferoxamine--pharmacology
Drug Synergism
Endothelium, Vascular--drug effects
Free Radical Scavengers--pharmacology
Glutathione--metabolism
Guinea Pigs
Heart Ventricles--drug effects
Hypertrophy, Left Ventricular--metabolism
In Vitro Techniques
Male
Malondialdehyde--metabolism
Metalloporphyrins--pharmacology
Myocardial Contraction--drug effects
NADPH Oxidases--metabolism
Oxidation-Reduction
Reactive Oxygen Species--metabolism
Substance P--pharmacology