Differential involvement of the sigma(1) (sigma(1)) receptor in the anti-amnesic effect of neuroactive steroids, as demonstrated using an in vivo antisense strategy in the mouse.

Maurice, T

Differential involvement of the sigma(1) (sigma(1)) receptor in the anti-amnesic effect of neuroactive steroids, as demonstrated using an in vivo antisense strategy in the mouse. [electronic resource] - British journal of pharmacology Dec 2001 - 1731-41 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0007-1188

10.1038/sj.bjp.0704355 doi


Amnesia--metabolism
Animals
Avoidance Learning--drug effects
Behavior, Animal--drug effects
Binding Sites
Blotting, Western
Brain--drug effects
Cerebral Cortex--drug effects
Dehydroepiandrosterone--pharmacology
Dizocilpine Maleate--pharmacology
Dose-Response Relationship, Drug
Hippocampus--drug effects
In Vitro Techniques
Learning Disabilities--chemically induced
Male
Maze Learning--drug effects
Memory--drug effects
Mice
Morpholines--pharmacology
Oligonucleotides, Antisense--pharmacology
Phenazocine--analogs & derivatives
Pregnenolone--pharmacology
Receptors, sigma--agonists
Sigma-1 Receptor