Targeted mutations in the syntaxin H3 domain specifically disrupt SNARE complex function in synaptic transmission.

Fergestad, T

Targeted mutations in the syntaxin H3 domain specifically disrupt SNARE complex function in synaptic transmission. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Dec 2001 - 9142-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1529-2401


Amino Acid Substitution
Animals
Animals, Genetically Modified
Antigens, Surface--genetics
Conserved Sequence--physiology
Drosophila
Embryo, Nonmammalian--physiology
Evoked Potentials--physiology
Gene Targeting
Genes, Lethal
Macromolecular Substances
Membrane Proteins--metabolism
Molecular Sequence Data
Mutagenesis, Site-Directed
Nerve Tissue Proteins--genetics
Neurons--metabolism
Neurotransmitter Agents--genetics
Phenotype
Protein Binding--physiology
Protein Structure, Tertiary--physiology
SNARE Proteins
Saline Solution, Hypertonic--pharmacology
Sequence Homology, Amino Acid
Structure-Activity Relationship
Synapses--metabolism
Synaptic Transmission--physiology
Syntaxin 1
Vesicular Transport Proteins