Progressive neuronal and motor dysfunction in mice overexpressing the serine protease inhibitor protease nexin-1 in postmitotic neurons.

Meins, M

Progressive neuronal and motor dysfunction in mice overexpressing the serine protease inhibitor protease nexin-1 in postmitotic neurons. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Nov 2001 - 8830-41 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1529-2401


Amyloid beta-Protein Precursor
Animals
Axons--pathology
Behavior, Animal
Brain--metabolism
Carrier Proteins--biosynthesis
Disease Progression
Electroencephalography
Evoked Potentials--genetics
Female
Gliosis--pathology
Male
Mice
Mice, Inbred C57BL
Mice, Neurologic Mutants
Mice, Transgenic
Motor Activity--genetics
Motor Neuron Disease--diagnosis
Motor Neurons--metabolism
Muscular Atrophy--genetics
Protease Nexins
Pyramidal Cells--metabolism
Receptor, Nerve Growth Factor
Receptors, Cell Surface
Receptors, Nerve Growth Factor--metabolism
Serine Proteinase Inhibitors--biosynthesis
Serpin E2
Spinal Cord--metabolism
Survival Rate
Weight Loss--genetics