Suppression of experimental myasthenia gravis, a B cell-mediated autoimmune disease, by blockade of IL-18.

Im, S H

Suppression of experimental myasthenia gravis, a B cell-mediated autoimmune disease, by blockade of IL-18. [electronic resource] - FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct 2001 - 2140-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1530-6860

10.1096/fj.01-0072com doi


Abatacept
Animals
Antibodies--therapeutic use
Antigens, CD
Antigens, Differentiation--biosynthesis
B-Lymphocytes--immunology
CD40 Ligand--metabolism
CTLA-4 Antigen
Cells, Cultured
Cytokines--biosynthesis
Disease Progression
Female
Hypersensitivity, Delayed--therapy
Immunoconjugates
Immunoglobulin G--biosynthesis
Interleukin-18--antagonists & inhibitors
Kinetics
Lymphocyte Activation
Myasthenia Gravis, Autoimmune, Experimental--immunology
Rats
Rats, Inbred Lew
Receptors, Nicotinic--immunology
T-Lymphocytes--immunology
Th1 Cells--immunology
Transforming Growth Factor beta--biosynthesis