Replacement of surgical castration by GnRH-inhibition or Leydig cell ablation in the male rat Hershberger antiandrogen assay.

Ashby, J

Replacement of surgical castration by GnRH-inhibition or Leydig cell ablation in the male rat Hershberger antiandrogen assay. [electronic resource] - Regulatory toxicology and pharmacology : RTP Oct 2001 - 188-203 p. digital

Publication Type: Journal Article

0273-2300

10.1006/rtph.2001.1506 doi


5-alpha Reductase Inhibitors
Androgen Antagonists--pharmacology
Animals
Body Weight--drug effects
Dichlorodiphenyl Dichloroethylene--pharmacology
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Finasteride--pharmacology
Flutamide--pharmacology
Gonadotropin-Releasing Hormone--antagonists & inhibitors
Hormone Antagonists--pharmacology
Hormone Replacement Therapy
Insecticides--pharmacology
Leydig Cells--physiology
Male
Mesylates--pharmacology
Oligopeptides--pharmacology
Orchiectomy
Organ Size--drug effects
Rats
Rats, Inbred Strains