Cyclin D1 overexpression induces progestin resistance in T-47D breast cancer cells despite p27(Kip1) association with cyclin E-Cdk2.

Musgrove, E A

Cyclin D1 overexpression induces progestin resistance in T-47D breast cancer cells despite p27(Kip1) association with cyclin E-Cdk2. [electronic resource] - The Journal of biological chemistry Dec 2001 - 47675-83 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0021-9258

10.1074/jbc.M106371200 doi


Animals
Blotting, Western
Breast Neoplasms--metabolism
CDC2-CDC28 Kinases
Cell Cycle Proteins--metabolism
Cell Division
Cyclin D1--biosynthesis
Cyclin E--biosynthesis
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p27
Cyclin-Dependent Kinases--metabolism
Dose-Response Relationship, Drug
Down-Regulation
Drug Resistance
Drug Resistance, Neoplasm
Flow Cytometry
G1 Phase
Phosphorylation
Precipitin Tests
Pregnenediones--pharmacology
Progesterone Congeners--pharmacology
Progestins--antagonists & inhibitors
Prognosis
Protein Binding
Protein Serine-Threonine Kinases--metabolism
Retroviridae--genetics
S Phase
Time Factors
Tumor Suppressor Proteins--metabolism