A novel 9-aza-anthrapyrazole effective against human prostatic carcinoma xenografts.

Supino, R

A novel 9-aza-anthrapyrazole effective against human prostatic carcinoma xenografts. [electronic resource] - Oncology 2001 - 234-42 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0030-2414

10.1159/000055380 doi


Adenocarcinoma--drug therapy
Animals
Anthraquinones--therapeutic use
Antigens, Neoplasm
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Division--drug effects
DNA Damage
DNA Topoisomerases, Type II--metabolism
DNA, Neoplasm--drug effects
DNA-Binding Proteins
Doxorubicin--therapeutic use
Ethanolamines--pharmacology
Gene Expression Regulation, Neoplastic--drug effects
Genes, bcl-2
Humans
Intercalating Agents--pharmacology
Male
Mice
Mice, Nude
Molecular Structure
Neoplasm Proteins--genetics
Oxidation-Reduction
Oxidative Stress
Phosphorylation
Prostatic Neoplasms--drug therapy
Protein Processing, Post-Translational--drug effects
Proto-Oncogene Proteins c-bcl-2--biosynthesis
Pyrazoles--pharmacology
Pyrazolones
Remission Induction
Xenograft Model Antitumor Assays