Apoptosis in podocytes induced by TGF-beta and Smad7.

Schiffer, M

Apoptosis in podocytes induced by TGF-beta and Smad7. [electronic resource] - The Journal of clinical investigation Sep 2001 - 807-16 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9738

10.1172/JCI12367 doi


Animals
Apoptosis--drug effects
Caspase 3
Caspases--metabolism
Cells, Cultured
DNA-Binding Proteins--pharmacology
Disease Models, Animal
Glomerular Mesangium--pathology
Glomerulosclerosis, Focal Segmental--etiology
Humans
Kidney Glomerulus--cytology
Mice
Mice, Transgenic
Mitogen-Activated Protein Kinases--metabolism
NF-kappa B--metabolism
Smad7 Protein
Trans-Activators--pharmacology
Transforming Growth Factor beta--genetics
p38 Mitogen-Activated Protein Kinases