Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation.

Solecki, D J

Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. [electronic resource] - Neuron Aug 2001 - 557-68 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0896-6273

10.1016/s0896-6273(01)00395-6 doi


Animals
Basic Helix-Loop-Helix Transcription Factors
Calcium-Binding Proteins
Cell Differentiation--physiology
Cell Division--physiology
Cells, Cultured
Cerebellar Cortex--cytology
Gene Expression Regulation, Developmental--drug effects
Green Fluorescent Proteins
Hedgehog Proteins
Homeodomain Proteins--genetics
Indicators and Reagents--metabolism
Intercellular Signaling Peptides and Proteins
Jagged-1 Protein
Luminescent Proteins--genetics
Membrane Proteins
Mice
Neurons--cytology
Proteins--genetics
RNA, Messenger--analysis
Receptor, Notch2
Receptors, Cell Surface--genetics
Retroviridae--genetics
Serrate-Jagged Proteins
Signal Transduction--physiology
Stem Cells--cytology
Trans-Activators--genetics
Transcription Factor HES-1
Transfection