Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation.

Osborne, A

Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. [electronic resource] - Molecular and cellular biology Oct 2001 - 6495-506 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0270-7306

10.1128/MCB.21.19.6495-6506.2001 doi


Butyrates--pharmacology
Chromatin--chemistry
DNA-Binding Proteins--metabolism
Deoxyribonuclease I--chemistry
Enzyme Inhibitors--pharmacology
Erythroid-Specific DNA-Binding Factors
HLA-DR Antigens--biosynthesis
Histone Deacetylase Inhibitors
Histone Deacetylases--metabolism
Host Cell Factor C1
Humans
Hydroxamic Acids--pharmacology
Interferon-gamma--pharmacology
Isobutyrates
Mutation
Nucleic Acid Conformation
Octamer Transcription Factor-1
Promoter Regions, Genetic
RNA, Messenger--biosynthesis
Repressor Proteins--antagonists & inhibitors
Retinoblastoma Protein--genetics
Transcription Factors--metabolism
Transcriptional Activation
Tumor Cells, Cultured
YY1 Transcription Factor