Dynamic platelet accumulation at the site of the occluded middle cerebral artery and in downstream microvessels is associated with loss of microvascular integrity after embolic middle cerebral artery occlusion.

Zhang, Z G

Dynamic platelet accumulation at the site of the occluded middle cerebral artery and in downstream microvessels is associated with loss of microvascular integrity after embolic middle cerebral artery occlusion. [electronic resource] - Brain research Sep 2001 - 181-94 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0006-8993

10.1016/s0006-8993(01)02735-4 doi


Animals
Blood Coagulation--physiology
Blood Platelets--cytology
Blood-Brain Barrier--physiology
Brain--enzymology
Brain Ischemia--enzymology
Cerebrovascular Circulation--physiology
Collagen Type IV--metabolism
Disease Models, Animal
Immunohistochemistry
In Vitro Techniques
Infarction, Middle Cerebral Artery--enzymology
Laminin--metabolism
Male
Matrix Metalloproteinase 2--metabolism
Matrix Metalloproteinase 9--metabolism
Matrix Metalloproteinases--metabolism
Microcirculation--pathology
Microscopy, Electron
Nonlinear Dynamics
Plasminogen Activator Inhibitor 1--metabolism
Platelet Glycoprotein GPIIb-IIIa Complex--metabolism
Rats
Rats, Wistar
Time Factors