Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell lines.

Weber, C K

Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell lines. [electronic resource] - Gastroenterology Sep 2001 - 657-67 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0016-5085

10.1053/gast.2001.27222 doi


Adult
Aged
Animals
Biglycan
Cell Cycle Proteins--analysis
Cyclin A--metabolism
Cyclin-Dependent Kinase Inhibitor p27
Extracellular Matrix Proteins
Female
G1 Phase--physiology
G2 Phase--physiology
Gene Expression Regulation, Neoplastic--drug effects
Humans
Male
Mice
Mice, Nude
Middle Aged
Neoplasm Transplantation
Pancreatic Neoplasms
Phosphorylation
Proliferating Cell Nuclear Antigen--metabolism
Proteoglycans--analysis
Proto-Oncogene Proteins p21(ras)--analysis
RNA, Messenger--analysis
Retinoblastoma Protein--analysis
S Phase--physiology
Stromal Cells--chemistry
Transforming Growth Factor beta--pharmacology
Transplantation, Heterologous
Tumor Cells, Cultured--chemistry
Tumor Suppressor Proteins