Synthesis, molecular modeling, and structure-activity relationship of benzophenone-based CAAX-peptidomimetic farnesyltransferase inhibitors.
Sakowski, J
Synthesis, molecular modeling, and structure-activity relationship of benzophenone-based CAAX-peptidomimetic farnesyltransferase inhibitors. [electronic resource] - Journal of medicinal chemistry Aug 2001 - 2886-99 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-2623
10.1021/jm010872r doi
Alkyl and Aryl Transferases--antagonists & inhibitors
Antineoplastic Agents--chemical synthesis
Benzophenones--chemical synthesis
Binding Sites
Cysteine--chemical synthesis
Enzyme Inhibitors--chemical synthesis
Humans
Models, Molecular
Molecular Mimicry
Peptide Fragments--chemistry
Structure-Activity Relationship
Tumor Cells, Cultured
Synthesis, molecular modeling, and structure-activity relationship of benzophenone-based CAAX-peptidomimetic farnesyltransferase inhibitors. [electronic resource] - Journal of medicinal chemistry Aug 2001 - 2886-99 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-2623
10.1021/jm010872r doi
Alkyl and Aryl Transferases--antagonists & inhibitors
Antineoplastic Agents--chemical synthesis
Benzophenones--chemical synthesis
Binding Sites
Cysteine--chemical synthesis
Enzyme Inhibitors--chemical synthesis
Humans
Models, Molecular
Molecular Mimicry
Peptide Fragments--chemistry
Structure-Activity Relationship
Tumor Cells, Cultured