Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis.

Feith, D J

Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis. [electronic resource] - Cancer research Aug 2001 - 6073-81 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0008-5472


9,10-Dimethyl-1,2-benzanthracene--toxicity
Animals
Biogenic Polyamines--metabolism
Carcinogens--toxicity
Cattle
Enzyme Induction--drug effects
Enzyme Inhibitors--metabolism
Keratin-15
Keratin-5
Keratins--genetics
Mice
Mice, Transgenic
Ornithine Decarboxylase--biosynthesis
Ornithine Decarboxylase Inhibitors
Promoter Regions, Genetic
Protein Biosynthesis
Proteins--genetics
Skin--drug effects
Skin Neoplasms--chemically induced
Tetradecanoylphorbol Acetate--toxicity