Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells.

Maggiolini, M

Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells. [electronic resource] - Molecular pharmacology Sep 2001 - 595-602 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0026-895X


Breast Neoplasms
Cell Division--drug effects
Dose-Response Relationship, Drug
Down-Regulation
Estrogen Receptor alpha
Estrogen Receptor beta
Estrogens, Non-Steroidal--pharmacology
Genistein--pharmacology
Humans
Isoflavones
Ligands
Phytoestrogens
Plant Preparations
Proteins--metabolism
Quercetin--pharmacology
RNA, Messenger--drug effects
Receptors, Estrogen--drug effects
Transcription, Genetic--drug effects
Trefoil Factor-1
Tumor Cells, Cultured
Tumor Suppressor Proteins
Up-Regulation