MMP inhibitors augment fibroblast adhesion through stabilization of focal adhesion contacts and up-regulation of cadherin function.

Ho, A T

MMP inhibitors augment fibroblast adhesion through stabilization of focal adhesion contacts and up-regulation of cadherin function. [electronic resource] - The Journal of biological chemistry Oct 2001 - 40215-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M101647200 doi


3T3 Cells
Animals
Antineoplastic Agents--metabolism
Cadherins--physiology
Cell Adhesion--physiology
Cell Compartmentation
Cell Transformation, Neoplastic
Cytoskeletal Proteins--metabolism
Extracellular Matrix--physiology
Fibroblasts--cytology
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
Focal Adhesions--physiology
Matrix Metalloproteinase Inhibitors
Matrix Metalloproteinases--metabolism
Mice
Models, Biological
Phosphorylation
Protease Inhibitors--metabolism
Protein Transport
Protein-Tyrosine Kinases--metabolism
Tissue Inhibitor of Metalloproteinase-1--metabolism
Trans-Activators
Up-Regulation
beta Catenin