Stereochemical, structural, and thermodynamic origins of stability differences between stereoisomeric benzo[a]pyrene diol epoxide deoxyadenosine adducts in a DNA mutational hot spot sequence.

Yan, S

Stereochemical, structural, and thermodynamic origins of stability differences between stereoisomeric benzo[a]pyrene diol epoxide deoxyadenosine adducts in a DNA mutational hot spot sequence. [electronic resource] - Journal of the American Chemical Society Jul 2001 - 7054-66 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0002-7863

10.1021/ja0043035 doi


7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide--chemistry
Adenine--chemistry
Base Sequence
Carcinogens, Environmental--chemistry
DNA Adducts--chemistry
Drug Stability
Humans
Intercalating Agents--chemistry
Models, Molecular
Mutagens--chemistry
Polycyclic Aromatic Hydrocarbons--chemistry
Stereoisomerism
Thermodynamics