The human IgG3 hinge mediates the formation of antigen dimers that enhance humoral immune responses to DNA immunisation.

Drew, D R

The human IgG3 hinge mediates the formation of antigen dimers that enhance humoral immune responses to DNA immunisation. [electronic resource] - Vaccine Jul 2001 - 4115-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0264-410X

10.1016/s0264-410x(01)00182-7 doi


Animals
Antibodies, Helminth--biosynthesis
Antigens, Helminth--chemistry
COS Cells
Dimerization
Epitopes, T-Lymphocyte
Female
Immunization
Immunoglobulin G--chemistry
Mice
Mice, Inbred BALB C
T-Lymphocytes, Helper-Inducer--immunology
Taenia--immunology
Vaccines, DNA--immunology
Vaccines, Synthetic--immunology