Relative contributions of cyclooxygenase- and cytochrome P450 omega-hydroxylase-dependent pathways to hypoxic dilation of skeletal muscle resistance arteries.

Frisbee, J C

Relative contributions of cyclooxygenase- and cytochrome P450 omega-hydroxylase-dependent pathways to hypoxic dilation of skeletal muscle resistance arteries. [electronic resource] - Journal of vascular research - 305-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1018-1172

10.1159/000051061 doi


Animals
Arachidonic Acid--metabolism
Arteries--physiopathology
Cyclooxygenase Inhibitors--pharmacology
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--metabolism
Endothelium, Vascular--physiopathology
Enzyme Inhibitors--pharmacology
Fatty Acids, Unsaturated--pharmacology
Hydroxyeicosatetraenoic Acids--biosynthesis
Hypoxia--physiopathology
Indomethacin--pharmacology
Male
Mixed Function Oxygenases--antagonists & inhibitors
Muscle, Skeletal--blood supply
NG-Nitroarginine Methyl Ester--pharmacology
Nitric Oxide Synthase--antagonists & inhibitors
Oxygen--blood
Prostaglandin-Endoperoxide Synthases--metabolism
Rats
Rats, Sprague-Dawley
Vascular Resistance
Vasodilation