Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes.

Helt, A M

Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes. [electronic resource] - Journal of virology Aug 2001 - 6737-47 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-538X

10.1128/JVI.75.15.6737-6747.2001 doi


Binding Sites
Binding, Competitive
Cell Cycle
Cell Cycle Proteins
Cells, Cultured
DNA Damage
DNA-Binding Proteins
E2F Transcription Factors
Gene Expression
Humans
Keratinocytes--cytology
Mutagenesis
Nuclear Proteins--metabolism
Oncogene Proteins, Viral--genetics
Papillomaviridae--metabolism
Papillomavirus E7 Proteins
Phosphoproteins--metabolism
Proteins
Recombinant Fusion Proteins--genetics
Retinoblastoma Protein--metabolism
Retinoblastoma-Like Protein p107
Retinoblastoma-Like Protein p130
Transcription Factors--genetics
Tumor Cells, Cultured